N-BOC-HEXAHYDRO-1H-AZEPIN-4-ONE Manufacturer CAS No.:188975-88-4

What is N-BOC-HEXAHYDRO-1H-AZEPIN-4-ONE Cas No.: 188975-88-4?

N-BOC-Hexahydro-1H-azepin-4-one is a chemical compound commonly used in organic synthesis, particularly in the field of medicinal chemistry.

Chemical Structure

1. N-BOC: The N-BOC group stands for N-tert-Butoxycarbonyl, a protecting group used in organic synthesis to temporarily protect the amine group during chemical reactions. We derive it from tert-butyl and carbonyl components and widely use it due to its stability and ease of removal under acidic conditions.
2. Hexahydro-1H-azepin-4-one: This part of the compound is a cyclic amine with a seven-membered ring (azepine) that has been fully hydrogenated (hexahydro). The “4-one” indicates a carbonyl group (a ketone) at the fourth position on the ring.

Main Application

1. Intermediate in Drug Synthesis: We primarily use N-BOC-Hexahydro-1H-azepin-4-one as an intermediate in the synthesis of various pharmaceutical compounds. The BOC group protects the amine during multi-step synthesis, allowing for selective reactions on other parts of the molecule. After these steps,  we can remove the BOC group to reveal the free amine. It is crucial for the biological activity of many drugs.

2. Peptide Synthesis: In peptide synthesis, we use the BOC group to protect amino groups to prevent unwanted side reactions. We utilize it to introduce a protected amine moiety into peptide chains or other complex molecules.

3. Building Block for Heterocyclic Compounds: The hexahydro-azepinone core is a versatile scaffold in the design of heterocyclic compounds, which are key components in many bioactive molecules. These compounds often exhibit a wide range of biological activities and are integral to the development of new drugs.

4. Chemical Synthesis Research: We use it in research and development within the chemical and pharmaceutical industries to explore new synthetic routes and create novel compounds with potential therapeutic applications.

Summary

N-BOC-Hexahydro-1H-azepin-4-one serves as a valuable tool in organic synthesis, especially in the preparation of pharmaceuticals. Its BOC-protected amine allows for selective and controlled chemical reactions, making it an essential intermediate in the synthesis of complex organic molecules.